Morphological changes of the visual analyzer and disturbance of visual-spatial perception in Parkinson’s disease

Abstract

Modern data about the etiopathogenesis of the considered symptoms is represented. The results of our own research with estimation of the thickness of the various layers of the retina, the cerebral cortex, clinical and neuropsychological examination of patients are presented. Examination of the retina and the thickness of the cerebral cortex were carried out using the technique of optical coherent tomography and magnetic resonance imaging of the brain, respectively. Clinical and neuropsychological testing, aimed at setting the degree of severity of the disease, the severity of visual-spatial and cognitive changes and their relationship were conducted. The data allow us to view the presence of the most sensitive areas of the retina and cerebral cortex in the development of visual-spatial impairment in Parkinson’s disease patients. Refs 37. Figs 3. Tabl. 4.