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http://hdl.handle.net/11701/34130
Полная запись метаданных
Поле DC | Значение | Язык |
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dc.contributor.author | Zolotovskaya, Elena | - |
dc.contributor.author | Nazarova, Anna | - |
dc.contributor.author | Saranchina, Alexandra | - |
dc.contributor.author | Mutin, Andrei | - |
dc.contributor.author | Drozdova, Polina | - |
dc.contributor.author | Lubyaga, Yulia | - |
dc.contributor.author | Timofeyev, Maxim | - |
dc.date.accessioned | 2022-01-12T12:43:09Z | - |
dc.date.available | 2022-01-12T12:43:09Z | - |
dc.date.issued | 2021-12 | - |
dc.identifier.citation | Zolotovskaya, E., Nazarova, A., Saranchina, A., Mutin, A., Drozdova, P., Lubyaga, Yu., and Timofeyev, M. 2021. Hemocyte proteome of the Lake Baikal endemic Eulimnogammarus verrucosus (Crustacea: Amphipoda) sheds light on immune-related proteins. Bio. Comm. 66(4): 290–301. | en_GB |
dc.identifier.other | https://doi.org/10.21638/ spbu03.2021.402 | - |
dc.identifier.uri | http://hdl.handle.net/11701/34130 | - |
dc.description.abstract | Hemocytes are cells circulating in the hemolymph and playing an important role in crustacean immunity. These cells not only function as phagocytes but also express immune compounds to the hemolymph. Here we obtained hemocyte proteome of the endemic amphipod (Amphipoda, Crustacea) Eulimnogammarus verrucosus from Lake Baikal, the first hemocyte proteome of an amphipod, using liquid chromatography/tandem mass spectrometry (LC-MS/MS). A total of 1152 unique proteins were discovered with LC-MS/MS. We discovered both proteins directly involved in the immune response, such as pattern recognition proteins (C-type lectins), and compounds with antimicrobial activity (ctenidin and anti-lipopolysaccharide factor/scygonadin). Moreover, hemocyanins which may act as a phenoloxidase and C-type lectins were among the most diverse protein groups in the hemocyte proteome. The obtained data can be useful for further studies of immune components and mechanisms in Baikal amphipods. | en_GB |
dc.description.sponsorship | The reported study was funded by Russian Foundation for Basic Research and the Government of the Irkutsk Region, project No. 20-44-383007. | en_GB |
dc.language.iso | en | en_GB |
dc.publisher | St Petersburg State University | en_GB |
dc.relation.ispartofseries | Biological Сommunications;Volume 66; Issue 4 | - |
dc.subject | hemocytes | en_GB |
dc.subject | LC-MS/MS | en_GB |
dc.subject | proteome | en_GB |
dc.subject | Lake Baikal | en_GB |
dc.subject | crustacean | en_GB |
dc.subject | amphipod | en_GB |
dc.subject | innate immunity | en_GB |
dc.subject | antimicrobial peptide | en_GB |
dc.subject | lectin | en_GB |
dc.title | Hemocyte proteome of the Lake Baikal endemic Eulimnogammarus verrucosus (Crustacea: Amphipoda) sheds light on immune-related proteins | en_GB |
dc.type | Article | en_GB |
Располагается в коллекциях: | Issue 4 |
Файлы этого ресурса:
Файл | Описание | Размер | Формат | |
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290-301.pdf | 2,35 MB | Adobe PDF | Просмотреть/Открыть |
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