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http://hdl.handle.net/11701/16210
Полная запись метаданных
Поле DC | Значение | Язык |
---|---|---|
dc.contributor.author | Mamon, Ludmila | - |
dc.contributor.author | Ginanova, Viktoria | - |
dc.contributor.author | Kliver, Sergey | - |
dc.contributor.author | Toropko, Mariya | - |
dc.contributor.author | Golubkova, Elena | - |
dc.date.accessioned | 2019-08-28T22:00:55Z | - |
dc.date.available | 2019-08-28T22:00:55Z | - |
dc.date.issued | 2019-06 | - |
dc.identifier.citation | Mamon, L., Ginanova, V., Kliver, S., Toropko, M., and Golubkova, E. 2019. Organ-specific transcripts as a source of gene multifunctionality: lessons learned from the Drosophila melanogaster sbr (Dm nxf1) gene. Bio. Comm. 64(2): 146–157. | en_GB |
dc.identifier.other | https://doi.org/10.21638/spbu03.2019.206 | - |
dc.identifier.uri | http://hdl.handle.net/11701/16210 | - |
dc.description.abstract | Analysis of the transcriptomes of different organisms has demonstrated that a single gene can have multiple transcripts. The sources of transcriptional variability are the alternative promoters, polyadenylation sites, splicing, and RNA editing. A comparison of the organisms of different taxa has demonstrated that the complexity of organization during evolution arises not due to an increase in the number of protein-coding genes. The greatest variability of transcripts is specific to the nervous and germinal systems. A variety of mechanisms providing for the complexity of the transcriptome ensures a precise and coordinated regulation of organ-specific functions through a combination of cis-acting elements and trans-acting factors. The D. melanogaster sbr (Dm nxf1) gene has proven to be an excellent model for investigating mechanisms potentially leading to the emergence of multiple products with various functions. | en_GB |
dc.description.sponsorship | This work was supported by the Russian Foundation for Basic Research (19-04-01255 а). | en_GB |
dc.language.iso | en | en_GB |
dc.publisher | St Petersburg State University | en_GB |
dc.relation.ispartofseries | Biological Communications;Volume 64; Issue 2 | - |
dc.subject | nxf (nuclear export factor) | en_GB |
dc.subject | D. melanogaster | en_GB |
dc.subject | alternative splicing | en_GB |
dc.subject | intron retention | en_GB |
dc.subject | transcriptional variability | en_GB |
dc.subject | alternative polyadenylation | en_GB |
dc.title | Organ-specific transcripts as a source of gene multifunctionality: lessons learned from the Drosophila melanogaster sbr (Dm nxf1) gene | en_GB |
dc.type | Article | en_GB |
Располагается в коллекциях: | Issue 2 |
Файлы этого ресурса:
Файл | Описание | Размер | Формат | |
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146-157.pdf | 659,19 kB | Adobe PDF | Просмотреть/Открыть |
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